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Currently, researchers only understand about 15 to 20 percent of the protein map, Veidner said. Still, he said that there are tools that allow scientists to feasibly predict the missing links.
Guney said that the disease that repurposed medicines target does not necessarily need to be related to the original illness, as long as the two have similar genes that are affected.
One example, he said, is sildenafil, known more commonly as viagra. Pharmacologists observed that the drug, initially used to cure heart conditions, had unrelated effects and started using it to treat erectile dysfunction.
“In the body, everything has multiple roles,” Panahi said. “If you try to do one thing, chances are… you’re going to affect a lot of other things while you’re trying to do that.”
Panahi, who aims to get into the field of drug development and discovery after graduation, was enthusiastic about treatments that target root causes as opposed to symptoms, and also advocated for a more holistic approach to treatment.
“Obviously, there’s a genetic predisposition, but there’s a lot you can do – living in less polluted areas, eating organic food [and] limiting your intake of red meat from antibiotic-raised animals,” Panahi said. “Just limiting the amount of chemicals entering your body limits the amount of free radicals and limits the amount of mistakes in your DNA.”
Photo courtesy Peter Kim, Creative Commons